GEDENLA: Genetic determinants of dengue fever in Sri Lanka
Approximately 40% of the world´s population live in regions endemic for dengue fever, particularly in the Asia-Pacific region. 50-100 million infections occur annually including 500,000 cases of potentially fatal dengue haemorrhagic fever (DHF).
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Pilot study in Sri Lanka
Lacking a sufficiently effective vaccine, improved understanding of this disease is a crucial prerequisite fort he development of novel approaches in diagnosis, treatment, and prevention. The project aims at establishing a new research partnership on neglected tropical diseases (NTDs) and on dengue in particular, thereby contributing to the control of these diseases in southern Asia. Components include the improvement of research and diagnostic capacities in Sri Lanka, training of young researchers, professional exchange, and a study on the role of genetic disposition for dengue virus infection and its manifestation.
Principal Investigator: Prof. Dr. med. Frank P. Mockenhaupt
Co-worker: Prabhanjan Gai
Cooperations: University of Peradeniya, Peradeniya, Sri Lanka
National Dengue Control Unit, Ministry of Health, Colombo, Sri Lanka
Robert Koch Institut, Berlin Karnataka Institute for DNA Research, Dharwad-Hubli, Indien
Tib Molbiol Syntheselabor, Berlin
Project duration: 2017-2019
Project status: Implementation